US National Library of Medicine. Other studies also show that endothelial dysfunction associated with Hashimoto’s Thyroiditis improves when taking alpha lipoic acid. Caution. In some cases, people may experience mild symptoms like nausea, rashes, or itching. You may report them to the FDA. doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. additional information. Alpha-lipoic acid may cause skin issues. advice about side effects. Alpha Lipoic Acid (ALA) is a mercury-chelating antioxidant. If I am always hungry, could it be diabetes. November 18, 2020, Medically In light of the above, and even if you are not taking other medications, it may be best to taper off alpha-lipoic acid, such as cutting to a half-dose for a week before stopping completely — although we are not aware of studies looking at this or other procedures for discontinuing alpha-lipoic acid treatment. Never ignore professional medical advice in seeking treatment because of something you have read on the WebMD Site. What are the side effects of Alpha-Lipoic acid? But these supplements could cause nausea, dizziness, or a rash. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Dec 2020), ASHP (updated 3 Dec 2020) and others. Alpha lipoic acid consumption during pregnancy can be safe. Although alpha lipoic acid is known to be safe for most adults, some people can be at a higher risk of suffering from adverse side effects. It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. Side effects only start to be felt at higher doses. Further Information about Alpha Lipoic Acid Side Effects. Side effects only start to be felt at higher doses. When taken at recommended doses, there are no harmful side effects to be expected. As a medicament, alpha lipoic acid has a detoxification effect if the body is poisonous or saturated with heavy metal salts. When taken at recommended doses, there are no harmful side effects to be expected. tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, Alpha Lipoic Acid - also known as Thioctic acid, Lipoic Acid or just ALA - is best known for being a powerful antioxidant, helping protect cells against harmful free radicals. It has the ability to regenerate and recycle other antioxidants such as Vitamins C and E and glutathione back to their previously active state to enhance and increase their function. Alpha Lipoic Acid Side Effects Although Alpha Lipoic Acid is generally considered very safe and well tolerated in healthy people, there are some side effects that have been associated with its use. received an overall rating of 4 out of 10 stars from 10 reviews. 8. US National Library of Medicine. Here is a brief breakdown of how consumption affects different individuals: ALA and Pregnant Women. Reviewed Signs of low blood sugar like dizziness, headache, feeling sleepy, feeling weak, shaking, a fast heartbeat, confusion, hunger, or sweating. There also has been no determination of a clear cut for long-term side effects that can result from taking Alpha Lipoic Acid. They are quite mild and can include skin rashes, abdominal pain, nausea, diarrhea, and vomiting. Oral and topical use do not cause adverse reactions, however injections—such as in the case of dermal fillers—are more likely to do so, but only rarely as a result of the product itself. If you drink a lot of alcohol and take alpha-lipoic acid too, you should take a thiamine supplement. Always read the product label for instructions and directions. Thyroid disease: Taking alpha-lipoic acid might interfere with treatments for under-active or over-active thyroid. This article provides information regarding the same. Here are 4 side effects of too much folic acid. Side effects only start to be felt at higher doses. Applies to alpha-lipoic acid: oral tablet. on. Mijnhout, G. The Netherlands Journal of Medicine, April 2010; vol 68: pp 158-160. 7. Alpha Lipoic Acid Side Effects Thyroid Alpha lipoic acid effect on inflammation and the inhibition of the NF-kB signaling pathways that signal the need for inflammation are lower when taking alpha lipoic acid. But these supplements could cause nausea, dizziness, or a rash. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. There have, in fact, been several reports of seizures and vomiting in children who have taken doses of 2,400 mg or greater.8 Common side effects of alpha-lipoic acid may include a headache, skin rash, muscle cramp, or a tingling "pins and needles" sensation… Other reported side effects include fatigue, insomnia, skin rash and diarrhea. Known as the “universal antioxidant,” ALA is found naturally inside every cell of the human body. Taking alpha-lipoic acid when there is a shortage of thiamine might cause serious health problems. Higher doses of alpha lipoic acid in healthy person can result in fatigue or upset stomach. Therefore, patients who undergo such treatment should consult with their doctor before. If you think you may have a medical emergency, immediately call your doctor or dial 911. “Alpha-lipoic acid in liver metabolism and disease”. Alpha lipoic acid, also known as ALA, doesn’t have many side effects, but the most common typically include low blood sugar and difficulty absorbing and retaining certain vitamins. Negative Alpha Lipoic Acid Side Effects. Although Alpha Lipoic Acid is generally considered very safe and well tolerated in healthy people, there are some side effects that have been associated with its use. It is a roll of the dice—a racing, distorted high or a severe, paranoid 1 low. Side effects only start to be felt at higher doses. If you drink a lot of alcohol and take alpha-lipoic acid too, you should take a thiamine supplement. When taken at recommended doses, there are no harmful side effects to be expected. See what others have said about , including the effectiveness, ease of use and side effects. Serotonin is a neurotransmitter involved with activation of the sympathetic nervous system, which is responsible for … Although beneficial for the health, it may have some side effects. Side effects only start to be felt at higher doses. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Heston on what are the side effects of alpha lipoic acid: High doses of Folic Acid might cause abdominal cramps, diarrhea, rash, sleep disorders, irritabilit, confusion, nausea, stomach upset, behavior changes, skin reactions, seizures, gas, and excitability. Many Alpha Lipoic Acid supplements on the market are in fact a mixture of the naturally occurring R-ALA and the cheaper synthetic version, or S-ALA. Studies have shown stabilized R-ALA to be up to 12 times more effective than S-ALA. What interactions can happen from taking alpha-lipoic acid? Further, taking alpha-lipoic acid when there is a deficiency of vitamin B1 (thiamine) might result in serious side effects and health issues as alpha lipoic acid reduces thiamine levels when consumed in high doses. Topical alpha-lipoic acid can also irritate the skin. In schizophrenia patients using AAPDs, lipoic acid reduced BMI (weight to height ratio) and total cholesterol levels [ 50 ]. Alpha-lipoic acid is a natural chemical that functions as an antioxidant throughout your body and helps regenerate other natural antioxidants. Alpha-lipoic acid is generally considered safe when taken as an oral supplement or used as a topical ointment. It may humiliate the efficiency of chemotherapy. See 11/18/2020, Memorial Sloan-Kettering Cancer Center web site, “About Herbs: Alpha-lipoic acid.”, Natural Medicines Comprehensive Database web site, “Alpha-lipoic acid.”, Natural Standard Patient Monograph, “Alpha-lipoic acid.”. Always Burden. Available for Android and iOS devices. 9. Side Effects. I have been having vertigo problems and my doctor put me on Meclazine but the vertigo comes and goes. If these more serious side effects occur, stop taking Alpha lipoic acid supplements and call your doctor. ALA might cause blood sugar levels to drop, so people with diabetes should consult with their health-care providers before taking it. This tool does not provide medical advice. None Adherence. Clinical research has shown no evidence of carcinogenic effects with administration of alpha lipoic acid. This is based on a study that looked at the effects of alpha lipoic acid on the production of reactive oxygen species, inflammation, and adipogenesis associated with Graves’ ophthalmopathy (19). Alpha-lipoic acid is considered possibly safe when taken orally by adults, when applied to the skin, as well as when taken intravenously. These side effects can include upset stomach, nausea, diarrhea, flatulence and the likes. R Alpha Lipoic Acid Side Effects and Precautions. I am 69 years old and I am type 2 Diabetic and I have hypertension. Some people who have taken alpha lipoic acid intravenously have also experienced some discomfort and redness at the site of the injection. But studies have suggested that its benefits go beyond free radical neutralization, and can extend to weight loss, diabetes (specifically, neuropathy) and skin damage. LSD is active mainly at certain serotonin receptor sub-types in the brain and body. One study found, however, that people taking alpha-lipoic acid orally may develop a rash (5). Fights Diabetes and Diabetic Complications. Alpha-lipoic acid should not be consumed by pregnant women. Minor side effects include skin reactions and gastrointestinal effects, such as nausea and vomiting. Side effects are uncommon. Reviewed Alpha lipoic acid supplements haven’t been studied in children or women who are pregnant or breastfeeding, so right now it’s intended for use in adults only. We comply with the HONcode standard for trustworthy health information -. THIS TOOL DOES NOT PROVIDE MEDICAL ADVICE. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Through research, and particularly through the extensive use of alpha lipoic acid in Europe, it can safely be said that side effects are very uncommon. It is intended for general informational purposes only and does not address individual circumstances. They are quite mild and can include skin rashes, abdominal pain, nausea, diarrhea, and vomiting. Alpha-lipoic acid is considered possibly safe when taken orally by adults, when applied to the skin, as well as when taken intravenously. Can you get alpha-lipoic acid naturally from foods? Although not all side effects are known, alpha-lipoic acid is thought to be possibly safe when taken as directed. This means that it mimics insulin in the body. Side effects of ALA supplementation are generally mild and include a skin rash. People deficient in thiamine, which is associated with long-term alcohol abuse, should not take alpha-lipoic acid 3. How Long Does Coronavirus Live On Surfaces? Thyroid disease: Taking alpha-lipoic acid might interfere with treatments for under-active or over-active thyroid. A small percentage of the population might also experience an allergic reaction to ALA or other ingredients included in supplement materials. Higher doses of ALA may result in increased heart palpitation, which in turn may cause fatigue. Speaking in general, there are no particular side effects with Alpha-Lipoic Acid consumption. Possible side effects Mild side effects of ALA can include itching. Alpha lipoic acid might benefit some people with thyroid eye disease. Call your doctor or get medical Taking alpha-lipoic acid when there is a shortage of thiamine might cause serious health problems. Although not serious, some of the minor side effects of taking the supplements are hives, allergic reaction, difficulty in breathing, swelling of the lips, tongue, etc. If you have questions about side effects, call your doctor. “Alpha Lipoic Acid”. Tell your There are few reported side effects of alpha lipoic acid when taken at dosage levels recommended by the suppliers. All rights reserved. Although beneficial for the health, it may have some side effects. However, a few have reported experiencing a rash, dizziness, and … The effect of alpha-lipoic acid in people with burning mouth syndrome is unclear. The Side Effects of Alpha Lipoic Acid. Although mild and quite rare side effects may include a rash, dizziness, and nausea. One study found, however, that people taking alpha-lipoic acid orally may develop a rash (5). However, a few have reported experiencing a rash, dizziness, and nausea, although only for a short time. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Side effects. Always speak with a medical professional or doctor before taking any supplements. Serious side effects have not been observed, even at high doses. Alpha-lipoic acid is generally considered safe with little to no side effects. Side effects are uncommon. Lipoic acid (possible overdose) may cause refractory convulsions in children [ 53 ]. Although not serious, some of the minor side effects of taking the supplements are hives, allergic reaction, difficulty in breathing, swelling of the lips, tongue, etc. Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; Alpha-Lipoic Side Effects. The … Vitamin N corrects cholesterol metabolism and improves the function of the hepar. The Side Effects of Alpha Lipoic Acid. Therefore, it’s important and highly recommended to use the … Alpha Lipoic Acid Side Effects. Clinical trials show using very high doses of alpha lipoic acid supplements (1800-2400 mg/day) for months caused no adverse side effects.Alpha lipoic acid has also been administered intravenously at 600-1200 mg/day without toxic side effects. Excessive intake of ALA can lead to the lowering of blood sugar. When taken at recommended doses, there are no harmful side effects to be expected. Side Effects of Hyaluronic Acid Side effects will vary depending on the application method. Pregnant women, among others, often take folic acid to increase their folate levels, but excessive intake may be damaging. Alpha lipoic acid is an antioxidant, or a natural, vitamin-like chemical. 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